產(chǎn)品名稱 |
產(chǎn)品編號(hào) |
規(guī)格 |
Recombinant Human IFN-beta Protein |
91221ES10 |
10 μg |
91221ES60 |
100 μg |
產(chǎn)品簡(jiǎn)介
干擾素家族的蛋白質(zhì)在誘導(dǎo)對(duì)廣泛的病毒感染的非特異性耐藥性方面發(fā)揮著重要作用。它們還影響細(xì)胞增殖并調(diào)節(jié)免疫反應(yīng)。IFN-α由外周血白細(xì)胞和淋巴母細(xì)胞產(chǎn)生,是一種酸穩(wěn)定分子,通過(guò)IFN-α/βR發(fā)出信號(hào),IFN-β也使用該分子。兩種IFN具有相似的抗病毒活性并調(diào)節(jié)MHC I類抗原的表達(dá)。I
本品重組人IFN-β是一種20.0kDa的蛋白質(zhì),含有166個(gè)氨基酸殘基。本品以液體形式提供,具有高活性,低內(nèi)毒素,無(wú)標(biāo)簽等特點(diǎn)。
性能參數(shù)
別名 |
Fibroblast interferon; IFB; IFBIFNB; IFF; IFNB; IFNB1; IFNbeta; IFN-beta; interferon beta |
Uniprot No. |
P01574 |
來(lái)源 |
HumanIFN-beta Protein is expressed from HEK293 without tag. It contains Met22-Asn187. |
分子量 |
The protein has a predicted 20.0 kDa |
純度 |
> 95% as determined by SDS-PAGE. |
生物活性 |
Measured in anti-viral assays using HeLa human cervical epithelial carcinoma cells infected with encephalomyocarditis (EMC) virus.The EC50 for this effect is 1-10 ng/mL. |
內(nèi)毒素 |
< 0.01 EU per 1μg of the protein by the LAL method. |
外觀 |
Liquid |
制劑 |
Dissolved in sterile PBS buffer. This solution can be diluted into other aqueous buffers. Centrifuge the vial prior to opening. |
儲(chǔ)存條件
-85~-65℃保存,收到貨之后有效期1年。
建議首次使用時(shí)將蛋白質(zhì)分裝,避免重復(fù)凍融循環(huán)。
注意事項(xiàng)
Ver. CN20240202