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      Recombinant Human MEC/CCL28  重組人MEC/CCL28
       
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      產(chǎn)品說明書
                  
      FAQ
                  
      COA
                  
      已發(fā)表文獻
                  
       
      MEC is a secreted CC chemokine expressed primarily by epithelial cells of the bronchioles, salivary gland, mammary gland and colon. MEC signals through the CCR10 receptor, and chemoattracts resting CD4, CD8 T-cells and eosinophils. MEC contains six cysteines, including the four highly conserved cysteine residues present in CC chemokines. Recombinant Human MEC is a 12.3 kDa protein containing 108 amino acid residues.
      


       
      


      Product Properties
      


      
	
		
      
			
			
      Synonyms
      
			      		
			
			
      CCK1
      
			      		
		
      
		
      
			
			
      Accession
      
			      		
			
			
      Q9NRJ3
      
			      		
		
      
		
      
			
			
      GeneID
      
			      		
			
			
      56477
      
			      		
		
      
		
      
			
			
      Source
      
			      		
			
			
      E.coli-derived Human MEC/CCL28 protein,Ser20-Try172.
      
			      		
		
      
		
      
			
			
      Molecular Weight
      
			      		
			
			
      Approximately  12.4 kDa.
      
			      		
		
      
		
      
			
			
      AA Sequence
      
			      		
			
			
      SEAILPIASS CCTEVSHHIS RRLLERVNMC RIQRADGDCD LAAVILHVKR RRICVSPHNH TVKQWMKVQA AKKNGKGNVC HRKKHHGKRN SNRAHQGKHE TYGHKTPY
      
			      		
		
      
		
      
			
			
      Tag
      
			      		
			
			
      None
      
			      		
		
      
		
      
			
			
      Physical Appearance
      
			      		
			
			
      Sterile Filtered White lyophilized (freeze-dried) powder.
      
			      		
		
      
		
      
			
			
      Purity
      
			      		
			
			
      > 97% by SDS-PAGE and HPLC analyses.
      
			      		
		
      
		
      
			
			
      Biological Activity
      
			      		
			
			
      Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human lymphocytes is in a concentration range of 1.0-10.0 ng/mL
      
			      		
		
      
		
      
			
			
      Endotoxin
      
			      		
			
			
      <1 EU/μg of protein as determined by LAL method.
      
			      		
		
      
		
      
			
			
      Formulation
      
			      		
			
			
      Lyophilized from a 0.2 μm filtered concentrated solution in 20 mM PB, pH 7.4, 130 mM NaCl.
      
			      		
		
      
		
      
			
			
      Reconstitution
      
			      		
			
			
      We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20°C. Further dilutions should be made in appropriate buffered solutions.
      
			      		
		
      
	      

      


       
      


      Shipping and Storage
      


      The products are shipped with ice pack and can be stored at -20℃ to -80℃ for 1 year.
      


      Recommend to aliquot the protein into smaller quantities when first used and avoid repeated freeze-thaw cycles.
      


       
      


      Cautions
      


      1. Avoid repeated freeze-thaw cycles
      


      2. For your safety and health, please wear lab coats and disposable gloves for operation.
      


      3. For research use only.
      


      HB220418
      


       
      

         
       
       
       
       
       
       
       
      400-6111-883