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      Recombinant FITC-Labeled Human EGFRVIII Protein, His-Avi Tag
       
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      產(chǎn)品說明書
                  
      FAQ
                  
      COA
                  
      已發(fā)表文獻(xiàn)
                  
       
      

       
      


      The epidermal growth factor receptor (EGFR) subfamily of receptor tyrosine kinases comprises four members: EGFR (HER1), ErbB2, ErbB3, and ErbB4. EGFRvIII is tumor specific, and has not been found in normal tissues. EGFRvIII is highly tumorigenic, and can cause aggressive tumor phenotype, with increased invasion, proliferation, angiogenesis, and evasion of apoptosis.
      


       
      


      產(chǎn)品性質(zhì)
      


      
	
		
      
			
			
      Synonyms
      
			      		
			
			
      ErbB; EC 2.7.10; EC 2.7.10.1; EGFR; mENA; LEGFR; ERBB; ERBB1; HER1; PIG61; NISBD2
      
			      		
		
      
		
      
			
			
      Accession
      
			      		
			
			
      NP_001333870.1
      
			      		
		
      
		
      
			
			
      Source
      
			      		
			
			
      Recombinant FITC-Labeled Human EGFRVIII Protein is expressed from HEK293 Cells with His tag and Avi tag at the C-terminal. It contains Leu25-Ser378.
      
			      		
		
      
		
      
			
			
      Molecular Weight
      
			      		
			
			
      The protein has a predicted MW of 41.6 kDa. Due to glycosylation, the protein migrates to 68-80 kDa based on Tris-Bis PAGE result.
      
			      		
		
      
		
      
			
			
      Purity
      
			      		
			
			
      > 95% as determined by SDS-PAGE.
      
			      		
		
      
		
      
			
			
      Endotoxin
      
			      		
			
			
      < 1.0 EU per 1μg of the protein by the LAL method.
      
			      		
		
      
		
      
			
			
      Formulation
      
			      		
			
			
      Supplied as from 0.22μm filtered solution in PBS (pH 7.4). 
      
			      		
		
      
	      

      


       
      


      運輸與保存方法
      


      The products are shipped with ice pack and can be stored at -80℃ for 1 year.
      


      Recommend to aliquot the protein into smaller quantities for optimal storage. Please avoid freeze-thaw cycles.
      


       
      


      注意事項
      


      1.For your safety and health, please wear lab coats and disposable gloves for operation.
      


      2.For research use only!
      


       
      

      


      產(chǎn)品數(shù)據(jù)
      


      SDS-PAGE
      


      


      FACS Data
      


      


      HB230120
      

         
       
       
       
       
       
       
       
      400-6111-883