Vinculin is a cytoskeletal protein that plays an important role in the regulation of focal adhesions and embryonic development. Three structural vinculin domains include an amino-terminal head, a short, flexible proline-rich region and a carboxy-terminal tail. In the inactive state, the head and tail domains of vinculin interact to form a closed confirmation. The open and active form of vinculin translocates to focal adhesions where it is thought to be involved in anchoring F-actin to the membrane and regulation of cell migration.

 

產(chǎn)品性質(zhì)

別名	VCL; Vinculin; Metavinculin
SwissProt ID	P18206
基因ID	7414
免疫原	Recombinant protein of human Vinculin
緩沖液	50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
分子量	Calculated MW: 124 kDa; Observed MW：124 kDa
克隆類型	Monoclonal Antibody
宿主	Rabbit
物種反應(yīng)	Human, Mouse, Rat
推薦應(yīng)用	WB, IHC-P
純化方式	Affinity Purified

 

應(yīng)用

稀釋比 WB：1/500-1/1000；IHC: 1/50-1/100;

 

儲存條件

-25~-15℃保存

 

注意事項

1. 避免反復(fù)凍融。

2. 本產(chǎn)品僅作科研用途。

2. 為了您的安全和健康，請穿實驗服并佩戴一次性手套操作。

 

產(chǎn)品數(shù)據(jù)

Western blot

 

 

Ver.CN20230915