SOD-2 is a homotetrameric manganese enzyme (also known as MnSOD) that functions in the mitochondrion. ROS are implicated in a wide range of degenerative processes, including Alzheimer’s disease, Parkinson’s disease and ischemic heart disease. Homozygous mutant mice, which lack SOD-2, exhibit dilated cardiomyopathy, accumulation of lipid in liver and skeletal muscle, metabolic acidosis, oxidative DNA damage and respiratory chain deficiencies in heart and skeletal muscle.
產(chǎn)品性質(zhì)
別名 |
IPOB; IPO-B; MNSOD; MVCD6; Mn-SOD; SOD2 |
SwissProt ID |
P04179 |
基因ID |
6648 |
免疫原 |
Synthetic peptide. |
緩沖液 |
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3. |
分子量 |
Calculated MW: 25 kDa; Observed MW: 25 kDa |
克隆類型 |
Polyclonal Antibody |
宿主 |
Rabbit |
物種反應(yīng) |
Human, Mouse,Rat, Monkey |
推薦應(yīng)用 |
WB |
純化方式 |
Affinity Purified |
應(yīng)用
稀釋比 WB:1/500-1/1000
儲存條件
-25~-15℃保存
注意事項
1. 避免反復(fù)凍融。
2. 本產(chǎn)品僅作科研用途。
3. 為了您的安全和健康,請穿實驗服并佩戴一次性手套操作。
產(chǎn)品數(shù)據(jù)
Western blot
Western blot analysis of SOD2 in 293, COS7, C6, 3T3 and HeLa lysates using SOD2 antibody.
Western blot analysis of SOD2 in HepG2 and Raw264.7 lysates using SOD2 antibody.
Western blot analysis of SOD2 in HepG2 and Raw264.7 lysates using SOD2 antibody.
Ver.CN20231025