This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix.

 

產(chǎn)品性質(zhì)

別名	PTK2; FAK; FAK1; Focal adhesion kinase 1; FADK 1; Focal adhesion kinase-related nonkinase; FRNK; Protein phosphatase 1 regulatory subunit 71; PPP1R71; Protein-tyrosine kinase 2; p125FAK; pp125FAK
SwissProt ID	Q05397
基因ID	5747
免疫原	A synthetic peptide of human FAK
緩沖液	50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
分子量	Calculated MW: 119 kDa; Observed MW：125 kDa
克隆類型	Monoclonal Antibody
宿主	Rabbit
物種反應(yīng)	Human, Mouse, Rat
推薦應(yīng)用	WB, IHC-F, IHC-P, ICC/IF, IP
純化方式	Affinity Purified

 

應(yīng)用

稀釋比 WB：1/500-1/1000；IHC: 1/50-1/100; IF: 1/50-1/200; IP:1/20

 

儲存條件

-25~-15℃保存

 

注意事項

1. 避免反復(fù)凍融。

2. 本產(chǎn)品僅作科研用途。

3. 為了您的安全和健康，請穿實驗服并佩戴一次性手套操作。

 

產(chǎn)品數(shù)據(jù)

Western blot

Immunocytochemistry

Immunohistochemistry

 

 

Ver.CN20230914