RUNX2 regulates the transcription of various genes including osteopontin, bone sialoprotein, and osteocalcin via binding to the core site of the enhancers or promoters.RUNX3/AML2 is a member of the Runt family of transcription factors. RUNX3 is important for the suppression of cell proliferation in the gastric epithelium, neurogenesis of the dorsal root ganglia, and T cell differentiation.

 

產(chǎn)品性質(zhì)

別名	RUNX1; AML1; RUNX2; OSF2; RUNX3; CBFA3
SwissProt ID	Q01196/Q13761/Q13950
基因ID	861/864/860
免疫原	A synthetic peptide of human RUNX1/2/3.
緩沖液	50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
分子量	Calculated MW: 49 kDa; Observed MW: 49 kDa
克隆類型	Monoclonal Antibody
宿主	Rabbit
物種反應(yīng)	Human, Mouse, Rat
推薦應(yīng)用	WB, IHC-F, IHC-P, ICC/IF, IP
純化方式	Affinity Purified

 

應(yīng)用

稀釋比 WB:1/500-1/1000; IHC: 1/50-1/100; IF:1/50-1/200; IP:1/20;

 

儲(chǔ)存條件

-25~-15℃保存

 

注意事項(xiàng)

1. 避免反復(fù)凍融。

2. 本產(chǎn)品僅作科研用途。

3. 為了您的安全和健康，請(qǐng)穿實(shí)驗(yàn)服并佩戴一次性手套操作。

 

產(chǎn)品數(shù)據(jù)
Western blot

Western blot analysis of RUNX1/2/3 in Jurkat, Rat Brain, C6, CHO-K1 lysates using RUNX1/2/3 antibody.

 

Western blot analysis of RUNX1/2/3 in RAW264.7 lysates using RUNX1/2/3 antibody.

 

Immunohistochemistry

Immunohistochemistry analysis of paraffin-embedded mouse colon using RUNX antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

 

Immunocytochemistry

Immunocytochemistry analysis of RUNX(green) in Jurkat using RUNX antibbody, and DAPI(blue).

 

Ver.CN20231016