Functions as cell surface receptor for TIMP1 and plays a role in the activation of cellular signaling cascades. Plays a role in the activation of ITGB1 and integrin signaling, leading to the activation of AKT, FAK/PTK2 and MAP kinases. Promotes cell survival, reorganization of the actin cytoskeleton, cell adhesion, spreading and migration, via its role in the activation of AKT and FAK/PTK2.
產(chǎn)品性質(zhì)
別名 |
CD63 antigen; CD63 |
SwissProt ID |
P41731 |
基因ID |
12512 |
免疫原 |
A synthetic peptide of mouse CD63. |
緩沖液 |
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA |
分子量 |
Calculated MW:26 kDa; Observed MW: 40-70 kDa |
克隆類型 |
Monoclonal Antibody |
克隆號 |
4G3 |
宿主 |
Rabbit |
物種反應(yīng) |
Human, Mouse |
推薦應(yīng)用 |
WB, IHC-P |
純化方式 |
Affinity Purified |
應(yīng)用
稀釋比 WB:1/500-1/1000; IHC:1/50-1/100;
儲存條件
-25~-15℃保存
注意事項(xiàng)
1. 避免反復(fù)凍融。
2. 本產(chǎn)品僅作科研用途。
3. 為了您的安全和健康,請穿實(shí)驗(yàn)服并佩戴一次性手套操作。
產(chǎn)品數(shù)據(jù)
Western blot
Western blot analysis of CD63 in RAW264.7 lysates using CD63 antibody.
Immunocytochemistry
Immunohistochemistry analysis of paraffin-embedded Mouse Kidney using CD63 antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
Ver.CN20231102