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      Estrogen Receptor alpha Rabbit mAb
       
      更多活動(dòng)更多優(yōu)惠，盡在翌圣商城》
       
       
       
      批量采購(gòu)， 請(qǐng)點(diǎn)擊詢(xún)價(jià)
       
       
      產(chǎn)品說(shuō)明書(shū)
                  
      FAQ
                  
      COA
                  
      已發(fā)表文獻(xiàn)
                  
       
       
      


      ER (estrogen receptor 1) a member of the steroid receptor superfamily, contains highly conserved DNA binding (DBD) and ligand binding domains (LBD). Through its estrogen-independent and estrogen-dependent activation domains (AF-1 and AF-2, respectively), ER regulates transcription by recruiting coactivator proteins and interacting with general transcriptional machinery. Phosphorylation provides an important mechanism to regulate ER activity. ER is phosphorylated on multiple sites.
      


       
      


      產(chǎn)品性質(zhì)
      


      
	
		
      
			
			
      別名
      
			      		
			
			
      ESR1; Era; Eralpha; Estrogen receptor; Estradiol receptor; ER-alpha; Estrogen receptor 1; NR3A1; ER; ESR; ESRA; Estrogen receptor alpha
      
			      		
		
      
		
      
			
			
      SwissProt ID
      
			      		
			
			
      P03372
      
			      		
		
      
		
      
			
			
      基因ID
      
			      		
			
			
      2099
      
			      		
		
      
		
      
			
			
      免疫原
      
			      		
			
			
      A synthetic peptide of human Estrogen Receptor alpha.
      
			      		
		
      
		
      
			
			
      緩沖液
      
			      		
			
			
      50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA.
      
			      		
		
      
		
      
			
			
      分子量
      
			      		
			
			
      Calculated MW: 66 kDa; Observed MW: 66 kDa
      
			      		
		
      
		
      
			
			
      克隆類(lèi)型
      
			      		
			
			
      Monoclonal Antibody
      
			      		
		
      
		
      
			
			
      宿主
      
			      		
			
			
      Rabbit
      
			      		
		
      
		
      
			
			
      物種反應(yīng)
      
			      		
			
			
      Human
      
			      		
		
      
		
      
			
			
      推薦應(yīng)用
      
			      		
			
			
      WB, IHC-F, IHC-P, ICC/IF, IP, ChIP
      
			      		
		
      
		
      
			
			
      純化方式
      
			      		
			
			
      Affinity Purified
      
			      		
		
      
	      

      


       
      


      應(yīng)用
      


      稀釋比 WB:1/500-1/1000; IHC:1/50-1/100; IF:1/50-1/200; IP:1/20;
      


       
      


      儲(chǔ)存條件
      


      -25~-15℃保存
      


       
      


      注意事項(xiàng)
      


      1. 避免反復(fù)凍融。
      


      2. 本產(chǎn)品僅作科研用途。
      


      3. 為了您的安全和健康，請(qǐng)穿實(shí)驗(yàn)服并佩戴一次性手套操作。
      


       
      


      產(chǎn)品數(shù)據(jù)
      


      Western blot
      


      


      Western blot analysis of Estrogen Receptor alpha in K562, HeLa lysates using Estrogen Receptor alpha antibody.
      


       
      


      Immunohistochemistry
      


      


      Immunohistochemistry analysis of paraffin-embedded Human breast cancer using Estrogen Receptor alpha antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
      


       
      


      Immunohistochemistry
      


      


      Immunocytochemistry analysis of Estrogen Receptor alpha(green) in MCF-7 using Estrogen Receptor alpha antibody, and DAPI(blue).
      


       
      


      Ver.CN20231017
      

         
       
       
       
       
       
       
       
      400-6111-883