產(chǎn)品簡(jiǎn)介

 

SN38 is the active metabolite of the chemotherapy drug irinotecan (Camptosar). It is  a topoisomerase I inhibitor, prevents the enzyme from properly resealing the DNA strands after they have been unwound, which leads to the accumulation of DNA damage.

 

產(chǎn)品性質(zhì)

 

來源	Monoclonal anti-SN38 antibody, is produced from a hybridoma which was obtained from a mouse immunized with SN38..
緩沖液	1×PBS, pH7.4.
克隆類型	Monoclonal Antibody
亞型	IgG1
宿主	Mouse
消光系數(shù)	1.4
濃度	1 mg/mL
純度	＞95% as determined by reduced SDS-PAGE ＞99% as determined by non-reduced SDS-PAGE > 99% as determined by SEC-HPLC
活性	EC50=80.5 ng/mL by ELISA
應(yīng)用	ELISA

 

儲(chǔ)存條件

 

-25~-15℃保存

 

注意事項(xiàng)

 

1. 避免反復(fù)凍融。

2. 本產(chǎn)品僅作科研用途。

3. 為了您的安全和健康，請(qǐng)穿實(shí)驗(yàn)服并佩戴一次性手套操作。

 

產(chǎn)品數(shù)據(jù) 

 

SDS-PAGE

 

SEC-HPLC

ELISA Data

 

Ver.CN20240726