產品簡介

 

DM1, also known as maytansine, is a microtubulin inhibitor, potentially conjugated with monoclonal antibodies to form antibody-drug conjugates(ADCs). DM1 as the toxin component of ADCs, exhibits strong anti-tumor activity by inhibiting cell division and inducing apoptosis.

 

產品性質

 

來源	Monoclonal anti-DM1 antibody, is produced from a hybridoma which was obtained from a mouse immunized with DM-1.
緩沖液	1×PBS, pH7.4.
克隆類型	Monoclonal Antibody
亞型	IgG1
宿主	Mouse
消光系數	1.4
濃度	1 mg/mL
純度	＞94% as determined by reduced SDS-PAGE ＞97% as determined by non-reduced SDS-PAGE > 98% as determined by SEC-HPLC
活性	EC50=8.6 ng/mL by ELISA
應用	ELISA

 

儲存條件

 

-25~-15℃保存

 

注意事項

 

1. 避免反復凍融。

2. 本產品僅作科研用途。

3. 為了您的安全和健康，請穿實驗服并佩戴一次性手套操作。

 

產品數據

 

SDS-PAGE

 

SEC-HPLC

ELISA Data

Ver.CN20240726