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      Recombinant Human 4-1BB/TNFRSF9(His Tag)
       
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      產(chǎn)品信息
      


      
	
		
      
			
			
      產(chǎn)品名稱
      
			      		
			
			
      產(chǎn)品編號
      
			      		
			
			
      規(guī)格
      
			      		
		
      
		
      
			
			
      Recombinant Human 4-1BB/TNFRSF9 (His Tag)
      
			      		
			
			
      93544ES25
      
			      		
			
			
      25 μg
      
			      		
		
      
		
      
			
			
      93544ES60
      
			      		
			
			
      100 μg
      
			      		
		
      
		
      
			
			
      93544ES76
      
			      		
			
			
      500 μg
      
			      		
		
      
		
      
			
			
      93544ES80
      
			      		
			
			
      1 mg
      
			      		
		
      
	      

      


       
      


      產(chǎn)品描述
      


      4-1BB, is also known as CD137, is a type 2 transmembrane glycoprotein receptor belonging to the TNF superfamily. CD137 can be expressed by activated T cells, but to a larger extent on CD8 than on CD4 T cells. In addition, CD137 expression is found on dendritic cells, B cells, follicular dendritic cells, natural killer cells, granulocytes and cells of blood vessel walls at sites of inflammation.
      


       
      


      產(chǎn)品性質(zhì)
      


      
	
		
      
			
			
      別名（Synonyms）
      
			      		
			
			
      CD137; TNFRSF9; 4-1BB ligand receptor; 41BB; 4-1BB; CDw137; FLJ43501; ILA; T cell antigen ILA
      
			      		
		
      
		
      
			
			
      Uniprot No.
      
			      		
			
			
      Q07011
      
			      		
		
      
		
      
			
			
      表達區(qū)間及表達系統(tǒng)（Source）
      
			      		
			
			
      HEK293 Cells-derived Human 4-1BB/TNFRSF9 Protein, Leu24-Gln186 with His tag at the C-terminal
      
			      		
		
      
		
      
			
			
      分子量(Molecular Weight)
      
			      		
			
			
      Approximately 18.1 kDa. Due to glycosylation, the protein migrates to 35-40 kDa based on Tris-Bis PAGE result.
      
			      		
		
      
		
      
			
			
      外觀(Physical Appearance）
      
			      		
			
			
      Sterile Filtered White lyophilized (freeze-dried) powder.
      
			      		
		
      
		
      
			
			
      純度（Purity）
      
			      		
			
			
      > 95% as determined by SDS-PAGE and HPLC
      
			      		
		
      
		
      
			
			
      活性（Activity）
      
			      		
			
			
      ELISA Data: Immobilized Human 4-1BB, His Tag at 1μg/mL (100 μL/Well) on the plate. Dose response curve for Human 4-1BB Ligand Trimer, hFc Tag with the EC50 of 5.7 ng/mL determined by ELISA.
      
			      		
		
      
		
      
			
			
      內(nèi)毒素（Endotoxin）
      
			      		
			
			
      < 1.0 EU per 1μg of the protein by the LAL method.
      
			      		
		
      
		
      
			
			
      制劑（Formulation）
      
			      		
			
			
      Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 5% trehalose is added as protectant before lyophilization.
      
			      		
		
      
		
      
			
			
      復溶（Reconstitution）
      
			      		
			
			
      Centrifuge tubes before opening. Reconstituting to a concentration more than 100 μg/mL is recommended (usually we use 1 mg/mL solution for lyophilization). Dissolve the lyophilized protein in distilled water.
      
			      		
		
      
	      

      


       
      


      運輸與保存方法
      


      冰袋運輸。-20℃至-80℃保存，一年有效期。
      


      復溶后，-20 至 -80°C，在未開封狀態(tài)下保存 3-6 個月。復溶后，2-8°C 保存 2-7 天。
      


      建議第一次使用時分裝凍存，避免反復凍融。
      


       
      


      注意事項
      


        
	
      1. 避免反復凍融。
        2. 
	
      2. 為了您的安全和健康，請穿實驗服并戴一次性手套操作。
        3. 
	
      3. 本產(chǎn)品僅作科研用途！
        4. 

      

      


       
      


      產(chǎn)品數(shù)據(jù)
      


      Tris-Bis PAGE 
      



      

      


      SEC-HPLC 
      



      

      


      ELISA Data
      



      

      


       
      


      HB240312
      


       
      

         
       
       
       
       
       
       
       
      400-6111-883