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      動(dòng)物實(shí)驗(yàn)系列產(chǎn)品-選購(gòu)指南

       
      選擇指南
       

       

       
      客戶(hù)案例
       

       

       
      客戶(hù)文獻(xiàn)
       

       

      人類(lèi)疾病的發(fā)展十分復(fù)雜,以人本身作為實(shí)驗(yàn)對(duì)象來(lái)深入探討疾病發(fā)生機(jī)制,推動(dòng)醫(yī)藥學(xué)的發(fā)展來(lái)之緩慢,借助于動(dòng)物模型的間接研究,可以有意識(shí)地改變那些在自然條件下不可能或不易排除的因素,以便更準(zhǔn)確地觀察模型的實(shí)驗(yàn)結(jié)果并與人類(lèi)疾病進(jìn)行比較研究,有助于更方便、更有效地認(rèn)識(shí)人類(lèi)疾病的發(fā)生發(fā)展規(guī)律,研究防治措施。

       

      選擇指南

      模型名稱(chēng)

      建模產(chǎn)品

      溶解試劑

      模型驗(yàn)證

      建模方法

      潰瘍性結(jié)腸炎

      DSSCat# 60316ES)

      蒸餾水

      糞便DNA提取試劑盒Cat#18820ES

      磁珠法48孔土壤 /

      糞便DNA提取試劑盒FA(預(yù)封裝)

      Cat#18528ES

      磁珠法土壤/糞便DNA提取試劑盒

      Cat#18526ES

      H&E染色Cat# 60524ES

      尿糞隱血檢測(cè)Cat# 60403ES

      AB-PAS染色液Cat# 60534ES)

      5.ASACat# 60317ES

      AOM(Cat#60751ES)

      柳氮磺吡啶Cat# 60320ES)

      5-氟尿嘧啶Cat# 51412ES)

      點(diǎn)擊詳情

      急性肝損傷

      TAACat# 60395ES)

      氯化鈉(Cat# 60372ES)

      H&E染色Cat# 60524ES

      Masson染色(Cat# 60532ES

      點(diǎn)擊詳情

      溶血性貧血

      APH(Cat# 60396ES)

      氯化鈉(Cat# 60372ES)

      H&E染色Cat# 60524ES

      點(diǎn)擊詳情

      胰腺炎

      ?;悄懰徕c(Cat# 60398ES)

       

      H&E染色Cat# 60524ES)

      點(diǎn)擊詳情

      雨蛙素Cat# 60321ES)

      氯化鈉(Cat# 60372ES)

      點(diǎn)擊詳情

      L-精氨酸Cat# 61302ES)

       

      點(diǎn)擊詳情

      糖尿病

      STZCat# 60256ES)

      檸檬酸一水Cat# 60347ES

      檸檬酸三鈉二水Cat# 60348ES

      STZ鏈脲佐菌素專(zhuān)用溶劑(Cat# 60750ES

      H&E染色Cat# 60524ES)

      點(diǎn)擊詳情

      阿脲 一水合物(Cat# 60331ES)

      氯化鈉(Cat# 60372ES)

      H&E染色Cat# 60524ES)

      點(diǎn)擊詳情

      帕金森

      魚(yú)藤酮

      (Cat# 60393ES)-粉末

      (Cat# 60394ES)-溶液

      DMSOCat# 60313ES)

      氯化鈉(Cat# 60372ES)

      /

      點(diǎn)擊詳情

      MPTP

      (Cat# 60388ES)-粉末

      (Cat# 60387ES)-溶液

      氯化鈉(Cat# 60372ES)

      /

      點(diǎn)擊詳情

      口腔癌

      4-NQOCat# 60392ES

      蒸餾水

      H&E染色Cat# 60524ES)

      點(diǎn)擊詳情

      胃癌

      MNNGCat# 60397ES)

      DMSOCat# 60313ES)

      H&E染色Cat# 60524ES)

      點(diǎn)擊詳情

      高血壓

      L-NAME hydrochloride

      Cat# 52302ES)

      蒸餾水

      氯化鈉(Cat# 60372ES)

      H&E染色Cat# 60524ES)

      點(diǎn)擊詳情

      Angiotensin II human

      Cat# 54041ES)

      Deoxycorticosterone Acetate

      Cat# 54344ES)

      類(lèi)風(fēng)濕關(guān)節(jié)炎

      弗氏完全佐劑(CFA)

      Cat# 60718ES)

      蒸餾水

      H&E染色Cat# 60524ES)

      點(diǎn)擊詳情

      弗氏不完全佐劑(IFA)

      Cat# 60719ES)

      活細(xì)胞長(zhǎng)期示蹤劑

      (可用于評(píng)估體內(nèi)/體外大分子對(duì)

      半透膜的通透性、心血管、微循環(huán)、

      細(xì)胞單層空隙/運(yùn)動(dòng)、灌注、

      細(xì)胞膜滲透性、細(xì)胞內(nèi)吞、

      結(jié)腸炎的研究)

      FITC-Dextran

      FITC-Dextran(MW 4000)

      Cat#61220ES)

      FITC-Dextran (MW 10000)

      Cat#61221ES)

      FITC-Dextran (MW 20000)

      Cat#61222ES)

      FITC-Dextran (MW 40000)

      Cat#61223ES)

      FITC-Dextran (MW 70000)

      Cat#61224ES)

      FITC-Dextran (MW 150000)

      Cat#61225ES) 

      蒸餾水

      PBS粉末Cat# 60158ES

      PBS液體Cat# 41403ES)

      氯化鈉(Cat# 60372ES)

       

      /

      點(diǎn)擊詳情

      Antonia Red-Dextran

      Antonia Red-Dextran(MW4000)

      Cat#61226ES)

      Antonia Red-Dextran(MW20000)

      Cat#61227ES)

      Antonia Red-Dextran(MW40000)

      Cat#61228ES)

      Antonia Red-Dextran(MW150000)

      Cat#61229ES)

      TRITC-Dextran

      TRITC-Dextran(MW4000)

      Cat#61230ES)

      TRITC-Dextran(MW20000)

      Cat#61231ES)

      TRITC-Dextran(MW40000)

      Cat#61232ES)

      TRITC-Dextran(MW70000)

      Cat#61233ES)

      TRITC-Dextran(MW150000)

      Cat#61234ES)

      TRITC-Dextran(MW500000)

      Cat#61235ES)

      TRITC-Dextran(MW2000000)

      Cat#61236ES)

      動(dòng)物麻醉劑

      2,2,2-Tribromoethanol(TBE)2,2,2-三溴乙醇

      Cat#60727ES)

      蒸餾水

       

      /

      /

      脂多糖(LPS)炎癥模型

      (急性肺損傷;急性胰腺炎;

      急性肝衰竭;牙周炎;敗血癥模型等)

      LPS,from Escherichia coli

      O55:B5 脂多糖來(lái)源于大腸桿菌O55:B5

      Cat#60747ES)

      LPS,from Escherichia coli

      O111:B4 脂多糖來(lái)源于大腸桿菌O111:B4

      Cat#60748ES)

      蒸餾水

      H&E染色Cat# 60524ES)

      阿利新藍(lán)-過(guò)碘酸雪夫(AB-PAS)染色液

      Cat# 60534ES)

      點(diǎn)擊詳情

       

       

       

       

      客戶(hù)案例

      1.DSS(Cat# 60316ES)——含硫量16-20%,游離硫<0.2%,模擬人UC模型,安全高效

      1 結(jié)腸炎H&E染色結(jié)果

       

      客戶(hù)1:

      客戶(hù)來(lái)源:南京農(nóng)業(yè)大學(xué)

      動(dòng)物類(lèi)型:C57BL/6小鼠

      造模方法:3% (w/v) DSS自由飲用7天

      引用自:doi.org/10.1016/j.jnutbio.2020.108438

      2 結(jié)腸癌H&E染色結(jié)果

      客戶(hù)2:

      客戶(hù)來(lái)源:暨南大學(xué)

      動(dòng)物類(lèi)型:BALB/c小鼠

      造模方法:

      1.10 mg/kg AOM處理小鼠后用純水自由飲1周;

      2.2.5%w/v)DSS自由飲用1周,換純水自由飲用2周;

      3.步驟2重復(fù)3次。

      引用自:doi: 10.3389/fphar.2020.586885

       

      2.雨蛙素(Cat# 60321ES)——十肽分子形式,純度(HPLC)≥97%

      3 胰腺H&E染色結(jié)果

      客戶(hù)3:

      客戶(hù)來(lái)源:上海交通大學(xué)醫(yī)學(xué)院

      實(shí)驗(yàn)動(dòng)物:Balb/c小鼠

      造模方法:1小時(shí)間隔腹腔注射7次50 μg/kg雨蛙素,并在最后一次同時(shí)注LPS (10 mg/kg)誘導(dǎo)SAP。

      引用自:doi.org/10.1016/j. ebiom.2022.103959

       

       

      3.STZ(Cat# 60256ES)——鏈脲佐菌素,純度(HPLC)≥98%

      4 各器官H&E染色結(jié)果

      客戶(hù)4:

      客戶(hù)來(lái)源:華中科技大學(xué)同濟(jì)醫(yī)學(xué)院

      引用自:DOI: 10.1021/acsami.1c24569

       

       

       

       

      客戶(hù)文獻(xiàn)

       

      向下滑動(dòng)查看

      [1] Li Zhao, Fei Wang,Zhengwei Cai,et al.Improving drug utilization platform with injectable mucoadhesive hydrogel for treating ulcerative colitis[J].chemical engineering journal.424(2021)130464.IF=16.744

      [2] Lingjun Tong, Haining Hao, Zhe Zhang,et al.Milk-derived extracellular vesicles alleviate ulcerative colitis by regulating the gut immunity and reshaping the gut microbiota[J].Theranostics.2021; 11(17): 8570-8586 IF=11.556

      [3] Li, Y., Dong, J., Xiao, H., Zhang, S., Wang, B., Cui, M., & Fan, S. Gut commensal derived-valeric acid protects against radiation injuries. Gut Microbes,.2020 .1–18.IF=10.245

      [4] Jingjing Gan, Yuxiao Liu, Lingyu Sun,et al.Orally administrated nucleotide-delivery particles from microfluidics for inflammatory bowel disease treatment[J].Applied Materials Today.2021 Dec;25:101231 IF=10.041

      [5] Mengmeng Xu, Ying Kong, Nannan Chen,et al.Identification of Immune-Related Gene Signature and Prediction of CeRNA Network in Active Ulcerative Colitis[J].Frontiers in Immunology.2022; 13: 855645. IF=7.561

      [6] JialiDong,YuanLi,HuiwenXiao,et al.Oral microbiota affects the efficacy and prognosis of radiotherapy for colorectal cancer in mouse models[J].Cell reports.2021, 109886.IF=9.423

      [7] Hao H,  Zhang X,  Tong L,  Liu Q,et al.Lactobacillus plantarumEffect of Extracellular Vesicles Derived From  Q7 on Gut Microbiota and Ulcerative Colitis in Mice[J].Frontiers in Immunology.2021.777147 .IF=7.561

      [8] Yaohua Fan,Yanqun Fan,Kunfeng Liu,et al.Edible Bird’s Nest Ameliorates Dextran Sulfate Sodium-Induced Ulcerative Colitis in C57BL/6J Mice by Restoring the Th17/Treg Cell Balance[J].Frontiers in Pharmacology.2021.632602.IF=7.561

      [9] Jia-Rong Huang, Sheng-Te Wang, Meng-Ning Wei,et al.Piperlongumine Alleviates Mouse Colitis and Colitis-Associated Colorectal Cancer[J].Frontiers in Pharmacology.2020.586885. IF=7.561

      [10] Gao X, Fan W, Tan L, et al. Soy isoflavones ameliorate experimental colitis by targeting ERα/NLRP3 inflammasome pathways[J]. The Journal of Nutritional Biochemistry, 2020, 83.IF=6.048

      [11] Lujuan Xing, Lijuan Fu, Songmin Cao,et al.The Anti-Inflammatory Effect of Bovine Bone-Gelatin-Derived Peptides in LPS-Induced RAW264.7 Macrophages Cells and Dextran Sulfate Sodium-Induced C57BL/6 Mice[J]. Nutrients 2022, 14, 1479. IF=5.717

      [12] Wang S,  Huang J,  Tan KS, et al.Isosteviol Sodium Ameliorates Dextran Sodium Sulfate-Induced Chronic Colitis through the Regulation of Metabolic Profiling, Macrophage Polarization, and NF-B Pathway[J].Oxidative Medicine and Cellular Longevity. 2022,4636618. IF=5.076

      [13] Xi Z, Ahmad E, Zhang W, et al. Dual-modified nanoparticles overcome sequential absorption barriers for oral insulin delivery. J Control  Release. 2022;342:1-13. doi:10.1016/j.jconrel.2021.11.045 IF=9.776
      [14] Xu Z, Liu Y, Ma R, et al. Thermosensitive Hydrogel Incorporating Prussian Blue Nanoparticles Promotes Diabetic Wound Healing via ROS Scavenging and Mitochondrial Function Restoration. ACS Appl Mater Interfaces. 2022;14(12):14059-14071. doi:10.1021/acsami.1c24569(IF:9.229)
      [15] Wu M, Huang J, Shi J, Shi L, Zeng Q, Wang H. Ruyi Jinhuang Powder accelerated diabetic ulcer wound healing by regulating Wnt/β-catenin signaling pathway of fibroblasts In Vivo and In Vitro. J Ethnopharmacol. 2022;293:115321. doi:10.1016/j.jep.2022.115321(IF:4.360)
      [16] Zhang Y, Zhang Y, Halemahebai G, Tian L, Dong H, Aisker G. Urolithin A, a pomegranate metabolite, protects pancreatic β cells from apoptosis by activating autophagy. J Ethnopharmacol. 2021;272:113628. doi:10.1016/j.jep.2020.113628(IF:3.690)
      [17] Wang M, Yang F, Yan X, et al. Anti-diabetic effect of banana peel dietary fibers on type 2 diabetic mellitus mice induced by streptozotocin and high-sugar and high-fat diet [published online ahead of print, 2022 Jun 29]. J Food Biochem. 2022;e14275. doi:10.1111/jfbc.14275(IF:2.720)
      [18] Liang H, Pan Y, Teng Y, et al. A proteoglycan extract from Ganoderma Lucidum protects pancreatic beta-cells against STZ-induced apoptosis. Biosci Biotechnol Biochem. 2020;84(12):2491-2498. doi:10.1080/09168451.2020.1805718(IF:2.043)

      [19] He R, Shi J, Xu D, et al. SULF2 enhances GDF15-SMAD axis to facilitate the initiation and progression of pancreatic cancer. Cancer Lett. 2022;538:215693. doi:10.1016/j.canlet.2022.215693(IF:8.679)
      [20] Zhang L, Shi J, Du D, et al. Ketogenesis acts as an endogenous protective programme to restrain inflammatory macrophage activation during acute pancreatitis. EBioMedicine. 2022;78:103959. doi:10.1016/j.ebiom.2022.103959(IF:8.143)
      [21] Yang X, Li R, Xu L, Qian F, Sun L. Serum amyloid A3 is required for caerulein-induced acute pancreatitis through induction of RIP3-dependent necroptosis. Immunol Cell Biol. 2021;99(1):34-48. doi:10.1111/imcb.12382(IF:5.126)
      [22] Li X, Ye C, Mulati M, Sun L, Qian F. Ellipticine blocks synergistic effects of IL-17A and TNF-α in epithelial cells and alleviates severe acute pancreatitis-associated acute lung injury. Biochem Pharmacol. 2020;177:113992. doi:10.1016/j.bcp.2020.113992(IF:4.960)
      [23] Xiao J, Feng X, Huang XY, et al. Spautin-1 Ameliorates Acute Pancreatitis via Inhibiting Impaired Autophagy and Alleviating Calcium Overload. Mol Med. 2016;22:643-652. doi:10.2119/molmed.2016.00034(IF:3.530)
      [24] Fan HN, Chen W, Fan LN, Wu JT, Zhu JS, Zhang J. Macrophages-derived p38α promotes the experimental severe acute pancreatitis by regulating inflammation and autophagy. Int Immunopharmacol. 2019;77:105940. doi:10.1016/j.intimp.2019.105940(IF:3.361)
      [25] Pu WL, Bai RY, Zhou K, et al. Baicalein attenuates pancreatic inflammatory injury through regulating MAPK, STAT 3 and NF-κB activation. Int Immunopharmacol. 2019;72:204-210. doi:10.1016/j.intimp.2019.04.018(IF:3.361)

       

       

       

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